2-Thiophenemethanamine, N-[(4-chlorophenyl)methyl]-5-nitro- - Names and Identifiers
2-Thiophenemethanamine, N-[(4-chlorophenyl)methyl]-5-nitro- - Physico-chemical Properties
Molecular Formula | C12H11ClN2O2S
|
Molar Mass | 282.75 |
Melting Point | >41°C (dec.) |
Solubility | Chloroform (Slightly), DMSO (Slightly) |
Appearance | Solid |
Color | Light Brown to Brown |
Storage Condition | -20°C Freezer, Under inert atmosphere |
2-Thiophenemethanamine, N-[(4-chlorophenyl)methyl]-5-nitro- - Upstream Downstream Industry
2-Thiophenemethanamine, N-[(4-chlorophenyl)methyl]-5-nitro- - Introduction
N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine(N-(4-chlorobenzyl)-1-(5-nitrothiophen-2-yl) methylamine) is an organic compound. It has a molecular formula of C15H13ClN2O2S and a molecular weight of 324.8g/mol.
The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine as a white crystalline solid.
-Melting point: The melting point range of this compound is 103-106 degrees Celsius.
-Solubility: It can be dissolved in organic solvents, such as ethanol and dimethylformamide.
Use:
-Pharmaceutical field: N-(4-Chlorobenzyl)-1-(5-Nitrothiophen-2-yl) methanamine is a synthetic intermediate commonly used in the preparation of biologically active organic compounds, such as Drugs and pesticides.
Preparation Method:
N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine was synthesized as follows:
1. react 2-chloronitrobenzene with ammonium thiocyanate to generate 2-nitrobenzenesulphonitrile.
2.2-nitrophenylthiononitrile and 2-nitrophenylthiamine are reacted in the presence of a base to generate 5-nitrothiophene-2-ol.
3. 5-nitrothiophen-2-ol and 4-chlorobenzyl bromide are reacted to generate N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine.
Safety Information:
The use and handling of-N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine requires attention to the general safe handling procedures of chemicals.
-It may be irritating to the eyes, skin and respiratory tract, so wear appropriate protective equipment when exposed.
-Avoid inhalation or ingestion of the compound and, if necessary, provide effective ventilation to ensure a safe working environment.
-When using or handling this compound, be sure to comply with local laws and regulations.
Please note that N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is a chemical. If you need to use or purchase it, it is recommended to consult a professional and strictly comply with relevant safety operations And regulations.
Last Update:2024-04-09 20:49:11